Carol de la Motte Ph.D. (Lerner Research Institute, Cleveland Clinic) Retired, Department of Pathobiology Interests: Studies the biosynthesis of hyaluronan and its impact in models of inflammation and fibrosis, specifically Crohn’s disease and pulmonary fibrosis.
Gerald W. Hart Ph.D. (CCRC, University of Georgia) Professor, Department of Biochemistry and Molecular Biology GRA William Henry Terry, Sr. Eminent Scholar in Drug Discovery
Interests: Studies the role of cytoplasmic and nuclear glycosylation in transcription, oncogene function, neurodegenerative disease, and in diabetes
Vincent Hascall Ph.D. (Lerner Research Institute, Cleveland Clinic)
Professor, Department of Biomedical Engineering
Interests: Studies how hyaluronan works in the setting of diabetes, wound healing, inflammatory bowel disease, certain cancers, as well as the lung diseases asthma and pulmonary hypertension.
Website: https://www.lerner.ccf.org/bme/hascall/
Telephone Number: 216-445-5676
Email Address: [email protected]
Ronald J. Midura Ph.D. (Lerner Research Institute, Cleveland Clinic)
Retired, Department of Molecular Medicine
Interests: The role of hyaluronan in wound healing and complications arising from obesity.
Website: https://www.lerner.ccf.org/bme/midura/
Ronald Schnaar Ph.D. (The Johns Hopkins University School of Medicine)
Professor, Departments of Pharmacology and Molecular Sciences & Neuroscience
Interests: Studying the impact of glycan interactions in inflammatory lung disease (Asthma, COPD, emphysema) and sialoglycans in the control of nervous system structure and function.
Website: https://www.hopkinsmedicine.org/schnaar/
Telephone Number: 410-955-8392
Email Address: [email protected]
Natasha Zachara Ph.D. (The Johns Hopkins University School of Medicine)
Associate Professor, Departments of Biological Chemistry & Oncology
Interests: Our laboratory is focused on understanding the role that the post-translational modification, O-GlcNAc, plays in mediating cytoprotective networks to affect survival in models of oxidative stress, ischemia reperfusion injury, and tumorigenesis.
Website: http://zacharalab.johnshopkins.edu/
Telephone Number: 410 955 7059
Email Address: [email protected]
Co-mentors - Cleveland Clinic
Serpil C. Erzurum, MD
Chief Research & Academic Officer, Cleveland Clinic
Chair, Lerner Research Institute
Email Address: [email protected]
Srinivasan Dasarathy M.D. (Lerner Research Institute, Cleveland Clinic)
Staff, Department of Inflammation and Immunity
Website: https://www.lerner.ccf.org/immuno/dasarathy/
Ed Maytin M.D. -Ph.D. (Lerner Research Institute, Cleveland Clinic)
Staff, Departments of Dermatology and Biomedical Engineering
Interests: Studies the impact of the extracellular matrix, especially hyaluronan, in wound healing.
Website: https://www.lerner.ccf.org/bme/maytin/
Co-mentors - Johns Hopkins University
Mark Anderson M.D. -Ph.D. (The Johns Hopkins University School of Medicine)
Physician in Chief and Director of the Department of Medicine
Interests: Research focuses on fundamental mechanisms of cellular signaling that contribute to cardiovascular diseases, heart failure, arrhythmias and sudden cardiac death.
Website: http://andersonlab.johnshopkins.edu/index.html
Jean Kim M.D. -Ph.D. (The Johns Hopkins University School of Medicine)
Associate Professor, Department of Otolaryngology - Head and Neck Surgery
Associate Professor, Department of Medicine- Division of Allergy and Clinical Immunology Interests: Translational research focuses on molecular mechanisms of eosinophilic airway inflammatory diseases, and mechanism of mucous production as key component of airway inflammatory disease in human airways. Website: https://www.hopkinsmedicine.org/research/labs/jean-kim-lab
Brian O’Rourke Ph.D. (The Johns Hopkins University School of Medicine)
Vice chair of Basic and Translational Research
Professor, Department of Medicine - Division of Cardiology Interests: His laboratory uses an integrated approach to study the biophysics, energetics and physiology of cardiac cells in normal and diseased states. His research is particularly interested in the interplay between ion gradients, redox/ROS balance and energy supply, which, when disrupted, can trigger nonlinear mitochondrial responses that scale to cause global cardiac dysfunction. Animal models and in vitro platforms for studying the mechanisms underlying heart failure, sudden cardiac death, ischemia-reperfusion injury, and metabolic disease are leveraged to develop new therapeutic approaches. Website: https://www.hopkinsmedicine.org/heart_vascular_institute/research/training_grant/orourke_lab/
Emeritus Co-mentors
Cleveland Clinic & Johns Hopkins School of Medicine
Mark A. Aronica M.D. (Lerner Research Institute, Cleveland Clinic)
Staff, Department of Pathobiology
Interests: Investigates the interactions between the extracellular matrix and cell signaling in pulmonary inflammation and injury.
Website: https://www.lerner.ccf.org/pathobio/aronica/
Telephone number: 216-445-3080
Email Address: [email protected]
George Muschler M.D. (Lerner Research Institute, Cleveland Clinic)
Staff, Department of Biomedical Engineering
Interests: Focused on advancing the field of tissue engineering through development of new strategies for preservation, repair, regeneration, augmentation, or replacement of musculoskeletal tissues.
Website: https://www.lerner.ccf.org/bme/muschler/
Telephone number: 216-444-5338
Email Address: [email protected]